Product Name: (Jianghuangsu)Turmeric Root Extract Other Name: Curcuma longa L. Appearance: Yellow fine Powder CAS NO: 485-37-7 MF: C21H20O6
Product Name:(Jianghuangsu)Turmeric Root Extract
Other Name: Curcuma longa L.
Appearance: Yellow fine Powder
Assay: 10%~ 95%
Test Method: HPLC
Physical Property: Melting point 179 ? -182 ?, do not soluble in water , soluble in methanol , ethyl acetate.
Turmeric Root Extract Curcumin Reviews
Turmeric is best known as a spice. It's one of the main components of curry powder. In India and other parts of Asia, turmeric is used to treat many health conditions. Curcumin, a substance in turmeric, may help to reduce inflammation. Several studies suggest that it might ease symptoms of osteoarthritis and rheumatoid arthritis, like pain and inflammation. Other compounds in turmeric might also be medicinal. Curcumin is also believed to have antioxidant, and perhaps even anticancer properties.
How Curcumin Works
Numerous studies evaluated that curcumin undergoes metabolism in different components after oral administration in animals. Because of its metabolism, curcumin has demonstrated poorly bioavailable after p.o. dosing in animals, which may be related to its inadequate absorption. Curcumin bioavailability may also be poor in humans, as indicated by a pilot study of a standardized curcuma extract in colorectal cancer patients. After p.o. dosing, curcumin undergoes metabolic O-conjugation to curcumin glucuronide and curcumin sulfate and bioreduction to tetrahydrocurcumin, hexahydrocurcumin, octahydrocurcumin, and hexahydrocurcuminol in rats and mice in vivo and in suspensions of human and rat hepatocytes. Reduced curcumin also subjected to glucuronidation into curcumin glucuronide,dihydro-curcumin-glucuronide, tetrahydrocurcumin-glucuronide, and curcumin sulfate. Holder et al. reported that the major billiarymetabolites of curcumin are glucuronides of tetrahydrocurcumin and hexahydrocurcumin in rats. A minor biliary metabolite was dihydroferulic acid together with traces of ferulic acid. Numerous studies have revealed that curcumin metabolites have antioxidative, anti-inflammatory and anticancer activities.Tetrahydrocurcumin (THC) inhibits radiationinduced lipid peroxidation and induced antioxidant enzymes in vitro. In rats, dietary administration of THC reduces aberrant crypt foci and polyps formation in azoxymethane-induced colon carcinogenesis.Hexahydrocurcumin, another metabolite, has reduced ability to inhibit COX-2 expression compared to curcumin. Hexahydrocurcumin also induce cell cycle arrest in human colorectal cancer SW480 cells. Pan et al. has shown that another metabolite,octahydrocurcumin, has very less NF-?B suppressive activity compared to curcumin. However, the free radical scavenging activity of octahydrocurcumin is higher than curcumin. Beside these, we have recently showed that none of curcumin mono- or di-glucurnoid showed biological activity such as anti-inflammatory or antiproliferative activity compared to curcumin. The curcumin metabolite,curcumin sulfate has shown to have less biological activities compared to curcumin. Curcumin sulfate inhibits prostaglandin E2activity very poor than curcumin. Thus these studies indicate that after metabolism of curcumin in different components, shows biological activities differ from parent curcumin.
Health Benefits of Turmeric Root Extract Curcumin
Curcumin is the major active component of turmeric, a yellow compound originally isolated from the plant
Curcuma longa. It is a member of the curcuminoid family and has been used for centuries in traditional medicines. As a spice, it provides curry with its distinctive color and flavor. Furthermore, traditional Indian medicine has considered curcumin a drug effective for various respiratory conditions(asthma, bronchial hyperactivity, and allergy) as well as for other disorders including anorexia, coryza, cough, hepatic diseases, and sinusitis. Extensive research over the past 30 years has shown that it plays an important role in the prevention and treatment of various pro-inflammatory chronic diseases including neurodegenerative, cardiovascular,pulmonary, metabolic, autoimmune and malignant diseases.
How curcumin could exhibit these diverse effects has been a clandestine over the years. However, numerous line of evidence
indicates that this agent is highly pleiotropic with anti-inflammatory, hypoglycemic, antioxidant, wound healing, and antimicrobial activities. It has been shown to possess chemosensitization, chemotherapeutic and radiosensitization activities as well. Curcumin has been studied for its chemopreventive potential in a wide variety of cancers, in both preclinical studies and in clinical trials. Many clinical trials using curcumin as a therapeutic agent are underway. Because of its marvelous properties, curcumin is being marketed in several countries including the United States, India, Japan, Korea, Thailand,China, Turkey, South Africa, Nepal, and Pakistan in different form such as capsules, tablets, ointments, energy drinks,soaps, and cosmetics.
Turmeric Root Extract Curcumin Side effects
Turmeric Root Extract Curcumin is POSSIBLY SAFE when used by mouth, short-term. But there is not enough known about the use of Curcumin during pregnancy and breast-feeding.
Turmeric Root Extract Curcumin dosage
The appropriate dose of Turmeric Root Extract Curcumin depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for Turmeric Root Extract Curcumin. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
Where to buy high quality Turmeric Root Extract Curcumin
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