Aug 15, 2019
Coenzyme Q10 not only provides power to the heart, but also has excellent anti-oxidation function, scavenging free radical, preventing lipid peroxidation in the blood vessel wall, and preventing atherosclerosis.
The specific role can be reflected in the following four aspects:
1. Protect the heart
Coenzyme Q10 helps to provide sufficient oxygen to the heart muscle which is a help to prevent sudden heart disease. Coenzyme Q10 plays a key role in the process of myocardial hypoxia improvement.
2.Protect the skin
Long-term use of Coenzyme Q10 can effectively prevent skin aging and reduce facial wrinkles.
Coenzyme Q10 keeps the cells in a healthy state, so the body is full of energy. The biological activity of coenzyme Q10 is mainly derived from the redox characteristics of its anthracene ring and the physicochemical properties of its side chain. Coenzyme Q10 is a natural antioxidant and cell metabolism promoter produced by the cell itself, which protects and restores the integrity of the biofilm structure and stabilizes the membrane potential. Coenzyme Q10 is a non-specific immunopotentiator of the body, and it shows excellent anti-fatigue effect.
Studies have shown that Coenzyme Q10 has an anti-tumor effect and has a certain clinical effect on advanced metastatic cancer. The basic physiological role of coenzyme Q10 is to assist cell energy supply and antioxidants.
Coenzyme Q10 is a kind of ubiquinone, which is about 500-1500mg in adults. It can be widely found in human organs, which exists in heart, kidney, liver, and muscle. It has two forms: oxidized coenzyme Q10 and reduced coenzyme Q10. These two forms can be transformed between each other. The oxidized coenzyme Q10 is mainly present in the mitochondria, participates in the tricarboxylic acid cycle and the decomposition of fat, and assists in the production of adenosine triphosphate (ATP), which directly supplies cells, thereby maintaining the normal physiological activities of the cells. All activities of the cells rely on ATP to provide energy. In the absence of oxidized coenzyme Q10, the energy supply of the cells will be problematic or even die. Reduced coenzyme Q10 is mainly found in damaged cells, lymph, and blood, and can absorb excess oxygen free radicals in these parts.
Oxygen-free radicals are intermediate metabolites in cell activity. A small amount of oxygen free radicals can help enhance immune function and regulate physiological functions, but excessive oxygen free radicals can destroy the structural function of cells. Coenzyme Q10 absorbs a part of oxygen radicals during the process from the reduced form to the oxidized form, which results in the antioxidant effect.
There are two main sources of coenzyme Q10 in the human body. The first one is self-synthesis, which is the main source. In vivo synthesis of coenzyme Q10 is carried out by tyrosine through at least 17 chemical processes with the participation of at least 7 vitamins (VB2, VB3, B6, B12, folic acid, VC and pantothenic acid) and some trace elements.
The second source is food. Because the content of coenzyme Q10 in food is generally low when the human body can synthesize, the exogenous coenzyme Q10 intake will decrease, and the coenzyme Q10 takes the lymph circulation system, which is destined to not absorb coenzyme Q10 from the food too much.
Coenzyme Q10 is formulated with both drugs and health supplements. As the drug, the Coenzyme Q10 drug has a capsule of 10 mg size and an injection of 5 mg size. It has been approved for adjuvant treatment of viral myocarditis, chronic heart failure, viral hepatitis, chronic active hepatitis, and cancer. Please note that it is ancillary treatment! And usually three times a day, 5-10mg each time, the overall dose is small, the effect is very limited. As a health care product, coenzyme Q10 has various specifications such as 50mg, 100mg, and 200mg. The dosage is generally 50-400mg, which is more than a dozen to hundreds of times. Although the health care product has a large dose specification and is convenient for large dose supplementation, it is limited by the influence of intestinal absorption, and the amount that can enter the body is still small. And when the human body does not lack coenzyme Q10, it will discharge excess metabolism.
It is difficult to determine its daily demand because Coenzyme Q10 can be synthesized by the body, and generally does not produce a deficiency. Its renewal time in the body is 50-125 hours, and a large part of the metabolized product is re-synthesized into coenzyme Q10, which is recycled by the body, so it is difficult to determine its daily demand.