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Pterostilbene VS Resveratrol

May 22, 2019


Pterostilbene is a potent antioxidant that helps improve your daily health by improving brain, heart and immune system functions. Pterostilbene improves cognition, lowers cholesterol, and increases insulin sensitivity.

Pterostilbene can also improve brain function and heart system, lowers blood sugar, fight cancer.


What is Pterostilbene?

Pterostilbene is found in almonds, grape leaves and vines, especially in blueberries. Its chemical structure is similar to resveratrol, a chemical found in wines.

Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene) is a naturally occurring compound found mainly in blueberries and Pterocarpus marsupium (PM). Depending on the intake of the fruit's rosewood, it is estimated that the amount of rosewood in each blueberry varies from 99 ng to 520 ng / g, depending on the type of berry ingested. There is ample evidence that Pterostilbene may have many preventive and therapeutic properties in a wide range of human diseases, including neurological, cardiovascular, metabolic and blood diseases. An effective anticancer agent for several malignant tumors has been reported in preclinical trials.


Pterostilbene VS Resveratrol

Pterostilbene is structurally similar to resveratrol. Resveratrol is a compound found in red wines that has considerable antioxidant, anti-inflammatory and anti-cancer effects; however, due to the presence of two The oxy group causes it to exhibit increased lipophilic and oral absorption, and Pterostilbene exhibits increased bioavailability. In animal studies, red sandalwood showed 80% bioavailability, while resveratrol was 20%, making it a potential advantage as a therapeutic.


What Are the Differences Between Pterostilbene and Resveratrol ?

Compared to Resveratrol, Pterostilbene contains two methoxy groups, which increases oral absorption and bioavailability.

The multiple benefits of Pterostilbene in the treatment and prevention of human diseases are attributed to its antioxidant, anti-inflammatory and anti-cancer properties, improved cellular function and inhibition of malignant cells.

Pterostilbene reduces Oxidative Stress and reactive oxygen species (ROS), such as hydrogen peroxide (H2O2) and superoxide anion (O2-), which are involved in several priming and pathogenesis-related disease processes. .


In addition, various cell lines treated with Pterostilbene showed antioxidant catalase, total glutathione (GSH), glutathione peroxidase (GPx), glutathione reductase Increased expression of glutathione reductase (GR) and superoxide dismutase (SOD).