Apr 11, 2019
The latest research shows that the combination of vitamin D and Omega-3 can improve the cognitive function and social behavior of children with ADHD, schizophrenia and two-way disorder. However, the exact mechanism of this is still unclear.
Dr. Bruce Ames, co-author of the study, is from the Oakland Institute Children's Hospital (CHORI). He noted that Omega-3, eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and vitamin D work synergistically to maintain normal levels of serotonin in the brain. The study showed that vitamin D can regulate serotonin synthesis, while EPA affects serotonin release, while DHA up-regulates serotonin receptor expression.
Researchers believe that low levels of serotonin in normal individuals are associated with antisocial behavior, uncontrollable violent behavior, and self-harm behavior. The study, published in the FASEB journal, also pointed out that women with less mental illness are due to the protective effects of estrogen: estrogen can increase the level of serotonin synthesis in the brain.
Daily supplementation with vitamin D and Omega-3: "feasible and meaningful"
Dr. Ames pointed out that many people with mental illness lack trace elements, especially vitamin D and Omega-3. “This also explains why daily supplementation with these trace elements can effectively treat children with ADHD, two-way disorders, schizophrenia, impulsive behavior, depression and obsessive-compulsive disorder.”
The study also pointed out that vitamin D is safer than Omega-3 supplementation and serotonin therapy. The latter usually has some side effects. According to NHS data, side effects of selective serotonin reuptake inhibitors (SSRIs) include anxiety, malignancy, and visual impairment. Researchers in many related fields also hope to have further clinical trials to obtain the optimal therapeutic dose of vitamin D, EPA and DHA for various specific psychiatric diseases. For the time being, this complementary treatment is very promising for success.
The deficiency of Vitamin D and Omega-3 are common in the United States and in certain populations, so complementary therapy is a very viable intervention and has a high therapeutic relevance. Studies have shown that approximately 70% of adults and 67% of children in the United States lack vitamin D. Dr. Harry Rice is the Vice President of the EPA and DHA Global Science Organization. He said: "I have known the important role of EPA and DHA in the serotonin pathway for many years, but I have never noticed the regulation of vitamin D in serotonin synthesis."
The study clarified that brain synthesis of serotonin requires adequate levels of vitamin D, equivalent to neurotransmitters to affect social behavior; the second part focuses on the role of Omega-3 and puts both Further research was conducted in specific disease patterns in children with ADHD, two-way disorders, schizophrenia, and impulsive behavior.